Campiglia’s research group develops analytical methods to separate, identify and quantify chemicals in natural and artificial materials. The new methodology has applications in environmental and forensic science, toxicology, and food science. Environmental methods make possible to track down the fate of highly toxic polycyclic aromatic compounds and their metabolic degradation products. The outcome of this research has improved our ability to understand and respond to the impacts of petroleum pollution in environmental ecosystems, such as the Gulf of Mexico. Additional achievements include the development of non-destructive methodology for the analysis of forensic fiber evidence; phosphorous sensing approaches for on-site analysis of urine and water samples; and chemical profiling with data mining techniques for organic food authentication and better understanding of drug trafficking networks. By following green chemistry principles, the end goal of Campiglia’s research program at UCF is to provide sustainable methods that bring direct benefits to society.